Welcome

We are a fresh, small bioinformatics group at the FSU Jena.

We focus on the development of algorithms and tools for handling large sequencing data sets. We apply our computational methods to de novo genome and transcriptome assembly, the comprehensive analysis of RNA-Seq data, and the identification of pathogens such as viruses.

We strive to combine well-established and novel computational approaches to analyze and visualize large amounts of short- and long-read sequencing data.

We work closely with the RNA Bioinformatics/High-Throughput group of Manja Marz and we are a member of the European Virus Bioinformatics Center.


Research Interests

  • Bioinformatics
  • Transcriptomics & comparative genomics
  • de novo assembly & annotation
  • Microbes & viruses
  • Metagenomics & -transcriptomics
  • Oxford Nanopore Sequencing
  • Non-coding RNA & RNA secondary structure
  • Automation & visualization







News

16. August 2019

Our tool PCAGO for the interactive analysis and visualization of RNA-Seq expression data (preprint) can now be simply used locally with the help of an Docker image. Thanks, Lasse!

13. August 2019

Bats are impressive! Our manuscript dealing with the RNA-Seq analysis of cells from a small bat species, Myotis daubentonii, got accepted in iScience! We investigated the transcriptome response to a viral infection or stimulation with interferon (IFN) at two time points. Many thanks to our partners at the Institute for Virology, JLU Giessen.

26. June 2019

Our manuscript about a new Chlamydia species isolated from a red-shouldered hawk got published in Systematic and Applied Microbiology! We are pleased that we were able to help with data evaluation and assembly to ultimately define this new species.

... see all News